Host Directed Therapeutics for the Prevention of Progression to ARDS
Solicitation Description
Proposal submissions are limited to respondents to the Request for Information released on 4/1/2026.
The objective of this RPP is to develop host directed therapeutics for the prevention of progression to acute respiratory distress syndrome (ARDS) in support of BARDA’s Influenza and Emerging Infectious Diseases Division (IEIDD). BARDA seeks Contractor(s) to support the continuation of the ARDS Preparedness and Response Program. This project supports advancing the late-stage clinical development of host-directed therapeutics for the prevention of progression to ARDS in hospitalized patients with viral respiratory infection who require supplemental oxygen.
Submission Information
All RRPV submissions must be submitted to the BARDA Digital Resources (BDR) RRPV Portal.
The account request process is simple but may take several days for approval and access. To request a BDR RRPV Portal account (first-time user), please complete the BDR Access Request Form. If you already have an account, please ensure you have access several days ahead of the submission deadline, if you have difficulty accessing your account please reach out to [email protected].
Documentation and reference materials for the BDR RRPV Portal are available to RRPV Member Organizations from the RRPV Members Only Site (for new users, request access here), and upon request from [email protected].
Neither the Government nor the RRPV CMF will make allowances/exceptions for submission problems encountered by the Offeror using system-to-system interfaces. If the Offeror fails to submit the full submission prior to the deadline, the submission may not be accepted. It is the Offeror’s responsibility to ensure a timely and complete submission. Failure to propose your submission on time for any reason may result in the submission not being considered for award.
Solicitation Details
Amendment 01:
Issued: 08 May 2026
Extends Due date; All other terms and conditions remain unchanged.
Original RPP Release:
Issued: 28 April 2026
Questions Due: 4 May 2026
Due: 26 May 2026 by 12pm ET