Opportunities

Active & Upcoming Solicitations

Closed Solicitations

RPP #TopicDescriptionSubmission Due Date
RFI: NMJ MPS Platforms for BoNT Potency Assay

Request for Information: Neuromuscular Junction (NMJ) Micro-Physiological Systems for Botulinum Neurotoxin (BoNT) Potency Measurement and Medical Countermeasures Evaluation

The Rapid Response Partnership Vehicle (RRPV) is issuing this Request for Information (RFI) to assess the current landscape of human-relevant neuromuscular junction (NMJ) micro-physiological systems (MPS) and their potential application for botulinum neurotoxin (BoNT) detection, potency measurement, and evaluation of medical countermeasure (MCM) neutralizing activity.11 May 2026 by 1 p.m. ET
RRPV RPP-26-10-RAPIDRapid Antibody Production for Immunoassay Diagnostics (RAPID)The purpose of this RPP is to support advanced research and development of rapid antibody or other protein-based molecular recognition reagents generation platforms to enable timely production of immunoassay-ready reagents to detect pathogens for eventual use in diagnostics. BARDA seeks highly flexible, rapidly adaptable systems capable of generating high-performance binders against pathogens, both known or previously unknown biological threats during public health emergencies.13 May 2026 by 1 p.m. ET
Coming SoonNew Vaccine Platforms (NVP)The New Vaccine Platforms (NVP) Program aims to identify new vaccine platforms for the BARDA medical countermeasure (MCM) portfolio and advance them through a staged capability demonstration to identify technologies that (1) are safe; (2) are effective across multiple infectious disease threats from different pathogen families; and (3) enable efficient development and manufacturing.TBD
RPP # (Date)Requirement TopicClosed Date
Request for Information: PreventARDS (4/1/2026)Host Directed Therapeutics for the Prevention of Progression to ARDS4/15/2026
RRPV RPP-26-07-ASSURE (11/14/2025)Assay Development for Superior Understanding of Response and Efficacy (ASSURE)2/24/2026
New Vaccine Platforms Request for Information (11/26/2025)New Vaccine Platforms1/30/2026
Rapid Antibody Production for Immunoassay Diagnostics (RAPID) Request for Information (10/31/2025)Rapid Antibody Production12/4/2025
RRPV RPP-26-09-AgDx (10/23/2025)Agnostic Diagnostics11/20/2025

RPP-25-06-DxR2
(5/29/2025)

Biothreat Diagnostic Rapid Response8/4/2025
RPP-24-07-CentralIEIDLab
(5/7/2025)
Central Influenza and Emerging Infectious Diseases Vaccine Immunoassay
Laboratory Services
5/30/2025
RPP-24-08-mRNALongTerm
(08/30/2024)
Rapid Pandemic Influenza and Emerging Infectious Disease Vaccine Development and Response Capability2/28/2025
RPP-24-02-OralVx
(09/09/2024)
NextGen Oral Formulation Vaccines for COVID-1911/15/2024
RPP-24-02-ODM
(08/13/2024)
On-Demand Manufacturing9/25/2024
RPP-24-03-SmMol
(08/05/2024)
COVID-19 Small Molecule Therapeutics for PrEP9/20/2024
RPP-24-06-DxR2
(3/27/2024)
Biothreat Diagnostic Rapid Response5/17/2024
RPP-24-03-Treatment
(02/21/2024)
Project NextGen: Therapeutics5/13/2024
RPP-24-05-NGClinMfg
(01/16/2024)
Project NextGen: Innovation in Clinical Manufacturing of COVID-19 Vaccines4/19/2024
RPP-24-04-NGVxStats
(2/23/2024)
NextGen Vaccines: Statistical Support, Correlates of Protection, and Meta-analysis3/27/2024
RPP-24-04-NGVxAssays 
(2/15/2024)
NextGen Vaccines: Immune Assays3/22/2024
RPP-24-02-Retail
(2/2/2024)
Enabling Technology – Decentralized Clinical Trial – Retail/Pharmacy Focus3/20/2024
RPP-24-03-PrEP
(11/30/2023)
COVID-19 Monoclonal Antibody Therapeutics for PrEP1/19/2024
RPP-24-02-HomeFocus
(11/30/2023)
Enabling Technology – Decentralized Clinical Trial – Home Focus1/19/2024
RPP-24-04-NGVx
(11/30/2023)
NextGen Vaccinations: Phase 2B Clinical Trial Execution1/10/2024

RPP-24-01-mRNA
(10/26/2023)

Accelerating Near-Term Availability of mRNA-based Pandemic Influenza Vaccine12/4/2023