Opportunities

Active & Upcoming Solicitations

Closed Solicitations

RPP #TopicDescriptionSubmission Due Date
Coming SoonNew Vaccine Platforms (NVP)The New Vaccine Platforms (NVP) Program aims to identify new vaccine platforms for the BARDA medical countermeasure (MCM) portfolio and advance them through a staged capability demonstration to identify technologies that (1) are safe; (2) are effective across multiple infectious disease threats from different pathogen families; and (3) enable efficient development and manufacturing.TBD
RPP # (Date)Requirement TopicClosed Date
RFI: PBD1 (6/3/2026)

Request for Information: Protection Before Day One Vaccine: Advancing Broadly Protective Seasonal Influenza Vaccines with Pandemic Coverage

7/29/2026
RFI: BSL4 (7/9/2026)

Request for Information: Biosafety Level 4 Preclinical and Nonclinical Support for Medical Countermeasure Development

7/24/2026

RFI: REDD (6/29/2026)

Request for Information: Repurposing Equipment for Drug Delivery

7/23/2026
RFI: HiPe (6/16/2026)Request for Information: High Performance Antigen Diagnostics7/17/2026

RFI: AdjEgg (6/24/2026)

Request for Information: Advanced Clinical Development and Licensure of an Adjuvanted Egg-based Influenza Vaccine7/10/2026
RPP-26-13-BundiVx (6/11/2026)Bundibugyo virus Outbreak Response Vaccines (BundiVx)7/2/2026
RFI Path(SM) (5/18/2026)Request for Information: AI-Enabled Discovery of Broad-Spectrum Small-Molecule Inhibitors for Filoviruses6/17/2026
RPP-26-12-ARDS (4/28/2026)Host-Directed Therapeutics for the Prevention of Progression to ARDS5/26/2026
RPP-26-10-RAPID (4/15/2026)Rapid Antibody Production for Immunoassay Diagnostics (RAPID)5/18/2026
RFI: NMJ MPS Plarforms for BoNT Potency Assay (4/20/2026)Request for Information: Neuromuscular Junction (NMJ) Micro-Physiological Systems for Botulinum Neurotoxin (BoNT) Potency Measurement and Medical Countermeasures Evaluation5/11/2026
Request for Information: PreventARDS (4/1/2026)Host Directed Therapeutics for the Prevention of Progression to ARDS4/15/2026
RPP-26-07-ASSURE (11/14/2025)Assay Development for Superior Understanding of Response and Efficacy (ASSURE)2/24/2026
New Vaccine Platforms Request for Information (11/26/2025)New Vaccine Platforms1/30/2026
Rapid Antibody Production for Immunoassay Diagnostics (RAPID) Request for Information (10/31/2025)Rapid Antibody Production12/4/2025
RPP-26-09-AgDx (10/23/2025)Agnostic Diagnostics11/20/2025

RPP-25-06-DxR2
(5/29/2025)

Biothreat Diagnostic Rapid Response8/4/2025
RPP-24-07-CentralIEIDLab
(5/7/2025)
Central Influenza and Emerging Infectious Diseases Vaccine Immunoassay
Laboratory Services
5/30/2025
RPP-24-08-mRNALongTerm
(08/30/2024)
Rapid Pandemic Influenza and Emerging Infectious Disease Vaccine Development and Response Capability2/28/2025
RPP-24-02-OralVx
(09/09/2024)
NextGen Oral Formulation Vaccines for COVID-1911/15/2024
RPP-24-02-ODM
(08/13/2024)
On-Demand Manufacturing9/25/2024
RPP-24-03-SmMol
(08/05/2024)
COVID-19 Small Molecule Therapeutics for PrEP9/20/2024
RPP-24-06-DxR2
(3/27/2024)
Biothreat Diagnostic Rapid Response5/17/2024
RPP-24-03-Treatment
(02/21/2024)
Project NextGen: Therapeutics5/13/2024
RPP-24-05-NGClinMfg
(01/16/2024)
Project NextGen: Innovation in Clinical Manufacturing of COVID-19 Vaccines4/19/2024
RPP-24-04-NGVxStats
(2/23/2024)
NextGen Vaccines: Statistical Support, Correlates of Protection, and Meta-analysis3/27/2024
RPP-24-04-NGVxAssays 
(2/15/2024)
NextGen Vaccines: Immune Assays3/22/2024
RPP-24-02-Retail
(2/2/2024)
Enabling Technology – Decentralized Clinical Trial – Retail/Pharmacy Focus3/20/2024
RPP-24-03-PrEP
(11/30/2023)
COVID-19 Monoclonal Antibody Therapeutics for PrEP1/19/2024
RPP-24-02-HomeFocus
(11/30/2023)
Enabling Technology – Decentralized Clinical Trial – Home Focus1/19/2024
RPP-24-04-NGVx
(11/30/2023)
NextGen Vaccinations: Phase 2B Clinical Trial Execution1/10/2024

RPP-24-01-mRNA
(10/26/2023)

Accelerating Near-Term Availability of mRNA-based Pandemic Influenza Vaccine12/4/2023