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Opportunities

OpportunitiesADMIN_DEMO32024-02-15T22:29:36-05:00
  • Active & Upcoming Solicitations

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  • Active & Upcoming Solicitations

RPP #

DescriptionRequiring OfficeSubmission Due Date
RPP 25-06-DxR2Biothreat Diagnostic Rapid Response

The DxR2 program will solicit new point of care/remote-use products with domestic manufacturing capabilities which address test development for Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) biothreats to include glanders, botulism, tularemia, typhus, smallpox, and plague.

The overall goals of this program are to build a biothreat diagnostic portfolio, maintain domestic test manufacturing facilities, and to enable just-in-time manufacturing practices to be able to rapidly produce biothreat tests and needed supplies at scale, and to achieve aggressive test delivery schedules. The first phase of the DxR2 program will focus on the development and regulatory clearance of biothreat tests, and design transfer to manufacturing activities, such as limited production runs for validation, quality checks, stability studies, early adopter training, and manufacturing capacity studies. Additional phases may be added dependent upon program progress and available funding.
July 14, 2025 1pm EST
Upcoming OpportunityPrize Administration for Innovation in Clinical Manufacturing

BARDA anticipates requesting project proposals for a partner(s) that has the expertise to design, promote, and administer effective prize competitions. With this prize approach, BARDA aims to spur participation from a broad range of organizations, including nontraditional private partners, to develop technical solutions that thrive beyond prize award.

The objective of the prize competitions would be to catalyze innovation in new manufacturing technologies that will improve access and enable faster, lower cost, rapid, and flexible production of medical countermeasures for health security threats.

BARDA anticipates to support at least two prizes through the Prize Administrator selected through this Request for Project Proposals (RPP).  The topics for those prizes are anticipated to be: (1) advance clinical testing of vaccines that leverage new GMP manufacturing approaches for single dose vaccines and (2) innovative approaches to improve the speed, yield, and scale up of non-vector/non nucleic acid-based vaccine manufacturing platforms (i.e., not RNA/DNA or viral-based) to enable rapid sequence-to-release of GMP clinical trial material in line with 100-day mission goals and Phase 1 testing.

Tentative Release Q2-Q3FY25
  • Closed Solicitations

RPP # (Date)Requirement TopicClosed Date
RPP-24-07-CentralIEIDLab
(5/7/2025)
Central Influenza and Emerging Infectious Diseases Vaccine Immunoassay
Laboratory Services
5/30/2025
RPP-24-08-mRNALongTerm
(08/30/2024)
Rapid Pandemic Influenza and Emerging Infectious Disease Vaccine Development and Response Capability2/28/2025
RPP-24-02-OralVx
(09/09/2024)
NextGen Oral Formulation Vaccines for COVID-1911/15/2024
RPP-24-02-ODM
(08/13/2024)
On-Demand Manufacturing9/25/2024
RPP-24-03-SmMol
(08/05/2024)
COVID-19 Small Molecule Therapeutics for PrEP9/20/2024
RPP-24-06-DxR2
(3/27/2024)
Biothreat Diagnostic Rapid Response5/17/2024
RPP-24-03-Treatment
(02/21/2024)
Project NextGen: Therapeutics5/13/2024
RPP-24-05-NGClinMfg
(01/16/2024)
Project NextGen: Innovation in Clinical Manufacturing of COVID-19 Vaccines04/19/2024
RPP-24-04-NGVxStats
(2/23/2024)
NextGen Vaccines: Statistical Support, Correlates of Protection, and Meta-analysis03/27/2024
RPP-24-04-NGVxAssays 
(2/15/2024)
NextGen Vaccines: Immune Assays3/22/2024
RPP-24-02-Retail
(2/2/2024)
Enabling Technology – Decentralized Clinical Trial – Retail/Pharmacy Focus03/20/2024
RPP-24-02-HomeFocus
(11/30/2023)
Enabling Technology – Decentralized Clinical Trial – Home Focus01/19/2024
RPP-24-03-PrEP
(11/30/2023)
COVID-19 Monoclonal Antibody Therapeutics for PrEP01/19/2024
RPP-24-04-NGVx
(11/30/2023)
NextGen Vaccinations: Phase 2B Clinical Trial Execution01/10/2024

RPP-24-01-mRNA
(10/26/2023)

Accelerating Near-Term Availability of mRNA-based Pandemic Influenza Vaccine12/4/2023
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